diff --git a/Source/Core/DolphinQt/Settings/GameCubePane.cpp b/Source/Core/DolphinQt/Settings/GameCubePane.cpp
index 8c5d306988..568230b3e0 100644
--- a/Source/Core/DolphinQt/Settings/GameCubePane.cpp
+++ b/Source/Core/DolphinQt/Settings/GameCubePane.cpp
@@ -726,7 +726,7 @@ void GameCubePane::LoadSettings()
     }
   }
 
-  m_skip_main_menu->setEnabled(have_menu);
+  m_skip_main_menu->setEnabled(have_menu || !m_skip_main_menu->isChecked());
   m_skip_main_menu->setToolTip(have_menu ? QString{} : tr("Put IPL ROMs in User/GC/<region>."));
 
   // Device Settings