diff --git a/rpcs3/Emu/system_config.cpp b/rpcs3/Emu/system_config.cpp
index 1136989d31..5ef5aeaa5d 100644
--- a/rpcs3/Emu/system_config.cpp
+++ b/rpcs3/Emu/system_config.cpp
@@ -1,9 +1,15 @@
 #include "stdafx.h"
 #include "system_config.h"
 #include "Utilities/StrUtil.h"
+#include "Utilities/sysinfo.h"
 
 cfg_root g_cfg;
 
+bool cfg_root::node_core::has_rtm() const
+{
+	return utils::has_rtm();
+}
+
 std::string cfg_root::node_vfs::get(const cfg::string& _cfg, const char* _def) const
 {
 	auto [spath, sshared] = _cfg.get();
diff --git a/rpcs3/Emu/system_config.h b/rpcs3/Emu/system_config.h
index d4097d036d..b0783eeaca 100644
--- a/rpcs3/Emu/system_config.h
+++ b/rpcs3/Emu/system_config.h
@@ -11,6 +11,11 @@ struct cfg_root : cfg::node
 {
 	struct node_core : cfg::node
 	{
+	private:
+		/** We don't wanna include the sysinfo header here */
+		bool has_rtm() const;
+
+	public:
 		static constexpr bool thread_scheduler_enabled_def =
 #ifdef _WIN32
 			true;
@@ -42,7 +47,7 @@ struct cfg_root : cfg::node
 		cfg::_bool spu_verification{ this, "SPU Verification", true }; // Should be enabled
 		cfg::_bool spu_cache{ this, "SPU Cache", true };
 		cfg::_bool spu_prof{ this, "SPU Profiler", false };
-		cfg::_enum<tsx_usage> enable_TSX{ this, "Enable TSX", tsx_usage::enabled }; // Enable TSX. Forcing this on Haswell/Broadwell CPUs should be used carefully
+		cfg::_enum<tsx_usage> enable_TSX{ this, "Enable TSX", has_rtm() ? tsx_usage::enabled : tsx_usage::disabled }; // Enable TSX. Forcing this on Haswell/Broadwell CPUs should be used carefully
 		cfg::_bool spu_accurate_xfloat{ this, "Accurate xfloat", false };
 		cfg::_bool spu_approx_xfloat{ this, "Approximate xfloat", true };
 		cfg::_bool llvm_accurate_dfma{ this, "LLVM Accurate DFMA", true }; // Enable accurate double-precision FMA for CPUs which do not support it natively
diff --git a/rpcs3/rpcs3qt/settings_dialog.cpp b/rpcs3/rpcs3qt/settings_dialog.cpp
index d62becfe6a..2db9b70178 100644
--- a/rpcs3/rpcs3qt/settings_dialog.cpp
+++ b/rpcs3/rpcs3qt/settings_dialog.cpp
@@ -231,6 +231,8 @@ settings_dialog::settings_dialog(std::shared_ptr<gui_settings> gui_settings, std
 		ui->enableTSX->setEnabled(false);
 		ui->enableTSX->addItem(tr("Not supported", "Enable TSX"));
 		SubscribeTooltip(ui->enableTSX, tr("Unfortunately your CPU model does not support this instruction set.", "Enable TSX"));
+
+		m_emu_settings->SetSetting(emu_settings_type::EnableTSX, fmt::format("%s", tsx_usage::disabled));
 	}
 
 	// PPU tool tips